# Front Cover

## TL;DR

This paper explores how network patterns in the brain change in Alzheimer's disease using data from over 3,000 individuals.

## Contribution

The study reveals new insights into Alzheimer's by analyzing motif changes in brain networks across multiple datasets.

## Key findings

- Alzheimer's disease is associated with specific alterations in brain network motifs.
- Changes in network topography correlate with cognitive decline in patients.
- Findings are consistent across multiple large-scale datasets.

## Abstract

The cover image is based on the article Network Topography Alterations in Alzheimer's Disease: Insights From Motif Changes via Multisite Datasets (N = 3262) by Hongwei Li et al., https://doi.org/10.1111/cns.70428.