# Successful Resection of Leiomyosarcoma Originating from the Inferior Vena Cava with Common Iliac Artery and Vein Reconstruction: A Case Report

**Authors:** Takashi Miyata, Koki Furuse, Saki Kuwata, Kaori Maruyama, Yuki Shinden, Shota Motoyama, Yuta Sannomiya, Hozumi Tamezawa, Taigo Nagayama, Hisashi Nishiki, Akifumi Hashimoto, Daisuke Kaida, Koichi Okamoto, Hideto Fujita, Nobuhiko Ueda, Daisuke Sakamoto, Yasuhiro Nagayoshi, Hiroyuki Takamura

PMC · DOI: 10.70352/scrj.cr.25-0008 · Surgical Case Reports · 2025-05-29

## TL;DR

A rare case of a leiomyosarcoma in the inferior vena cava was successfully removed with reconstruction of nearby blood vessels.

## Contribution

This case report demonstrates the feasibility of curative surgery for a rare leiomyosarcoma involving the inferior vena cava and aorta.

## Key findings

- The tumor was successfully resected with negative surgical margins.
- Reconstruction of the inferior vena cava and aorta was achieved using artificial blood vessels.
- The case highlights that curative surgery is possible despite tumor invasion into vital structures.

## Abstract

Leiomyosarcomas originating from the inferior vena cava are extremely rare. Because they have a strong tendency to invade the surrounding vital structures, cure can only be achieved by R0 resection.

A 59-year-old Japanese woman was referred to our hospital because an abdominal tumor had been detected on a routine ultrasound examination. Computed tomography revealed a 7.0 × 5.3 cm lesion occluding the inferior vena cava to the confluence of the common iliac vein and creating a mass effect on the adjacent aorta and common iliac artery bifurcation. After an open biopsy had yielded a diagnosis of leiomyosarcoma, radical surgery was planned. The tumor was excised en bloc together with the inferior vena cava and abdominal aorta and reconstruction performed using artificial blood vessels. Histopathological examination of the resected specimen confirmed it was a leiomyosarcoma originating from the inferior vena cava and invading the aorta and that the surgical margins were negative.

This report of a rare case of a leiomyosarcoma originating from the inferior vena cava and invading the aorta emphasizes that this combination of pathologies does not preclude curative surgery. However, more data are needed. Further research on leiomyosarcomas is essential for optimizing management and prognosis.

## Linked entities

- **Diseases:** Leiomyosarcoma (MONDO:0005058)

## Full-text entities

- **Diseases:** tumor (MESH:D009369), abdominal tumor (MESH:D000008), Leiomyosarcoma (MESH:D007890)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12129700/full.md

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Source: https://tomesphere.com/paper/PMC12129700