# Transforming the future of health: building learning health systems across the globe

**Authors:** Sandra Yankah, Robert Saunders, Mark Tykocinski, Claudia Salzberg, Jonathan Gonzalez-Smith, Rachel Bonesteel, Cameron Joyce, Charles Kahn, Mark McClellan, Eyal Zimlichman

PMC · DOI: 10.1093/haschl/qxaf103 · Health Affairs Scholar · 2025-05-21

## TL;DR

This paper outlines strategies for healthcare leaders to build learning health systems using data and AI, focusing on global collaboration and patient engagement.

## Contribution

The paper presents consensus-driven key action areas from international health leaders for advancing learning health systems.

## Key findings

- Healthcare leaders should leverage data and AI to support clinical decision-making.
- Creating a culture of learning within organizations is essential for adapting to health system challenges.
- Engaging patients and caregivers is critical for successful implementation of learning health systems.

## Abstract

Health care has faced disruptions over the past 5 years, including a global pandemic, supply chain interruptions, workforce shifts, and the introduction of new artificial intelligence (AI) tools. Health care organizations continue to leverage the learning health system (LHS) concept to adapt to these challenges through iterative feedback loops. The Future of Health (FOH), an international community of over 50 senior health leaders that focuses on shared challenges across international health systems, collaborated with the Duke-Margolis Institute for Health Policy in a consensus-building process with FOH members to identify opportunities for action in an LHS. Key areas for action identified include opportunities to leverage data and AI to support clinical decision-making, steps to create an organizational culture of learning, and strategies to engage patients and caregivers, illustrated through case examples.

What can health care leaders do to accelerate learnings and scale evidence-based interventions? This commentary describes 3 key areas for action from international health care leaders.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

33 references — full list in the complete paper: https://tomesphere.com/paper/PMC12128919/full.md

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Source: https://tomesphere.com/paper/PMC12128919