# Coagulopathy as a Complication of Cardiopulmonary Arrest Following Balloon Valvuloplasty in a Dog

**Authors:** Marissa A. Turner, Theresa C. Hallowell

PMC · DOI: 10.1002/vms3.70445 · Veterinary Medicine and Science · 2025-06-02

## TL;DR

A young dog developed a dangerous blood clotting disorder after a heart procedure and was successfully treated with blood transfusions and critical care.

## Contribution

First veterinary case report of coagulopathy and presumed DIC after cardiopulmonary arrest during balloon valvuloplasty.

## Key findings

- The dog experienced coagulopathy and presumed DIC following cardiac arrest during a valvuloplasty.
- Massive transfusion therapy and critical care led to successful recovery and significant improvement in heart function.
- Postoperative echocardiograms showed over 50% improvement in pulmonic valve pressure gradients.

## Abstract

To describe successful management of a coagulopathy secondary to cardiopulmonary arrest (CPA) associated with pulmonary balloon valvuloplasty.

An 8‐month‐old male intact Chihuahua mix presented for a pulmonary balloon valvuloplasty. Echocardiogram showed severe valvular pulmonic stenosis with a pulmonic valve maximum pressure gradient (PV max ΔP) of 108.2 mmHg (PV max ΔP >20 mmHg is considered abnormal). Near the end of the procedure, after the balloon deflation, the patient experienced prolonged periods of sinus arrest with associated ventricular escape rhythm. This was followed by complete sinus arrest and asystole. Cardiopulmonary resuscitation (CPR) was initiated. After four CPR cycles, return of spontaneous circulation was achieved. The patient continued to have hypotension despite fluid resuscitation, requiring vasopressor therapy. Hemorrhagic abdominal effusion was identified. Coagulopathy was confirmed via prolonged blood clotting times and thrombocytopenia. Treatment was comprehensive, including transfusions of whole blood, packed red blood cells and fresh frozen plasma. During 4 days of postoperative hospitalisation, the patient showed improvement and was discharged. Upon rechecking 13 and 227 days after discharge, a repeated echocardiogram showed a >50% improvement of the PV max ΔP measured at 40 and 38.5 mmHg, respectively.

This is the first published veterinary case report describing the recognition and successful treatment of a consumptive coagulopathy and presumptive disseminated intravascular coagulation (DIC) following CPA during a balloon valvuloplasty procedure.

An 8‐month‐old dog developed a consumptive coagulopathy and presumptive DIC following cardiac arrest during a balloon valvuloplasty procedure. Successful management required massive transfusion therapy and critical care.

## Linked entities

- **Diseases:** pulmonic stenosis (MONDO:0009938), coagulopathy (MONDO:0001531), disseminated intravascular coagulation (MONDO:0001243), hypotension (MONDO:0005468)

## Full-text entities

- **Diseases:** DIC (MESH:D004211), hypotension (MESH:D007022), CPA (MESH:D006323), Coagulopathy (MESH:D001778), thrombocytopenia (MESH:D013921), valvular pulmonic stenosis (MESH:D011666), sinus arrest (MESH:D054138), Hemorrhagic abdominal effusion (MESH:D000007), UNIQUE (MESH:C566733)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

30 references — full list in the complete paper: https://tomesphere.com/paper/PMC12128459/full.md

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Source: https://tomesphere.com/paper/PMC12128459