# Definitive Surgical Management of Refractory Amiodarone-Induced Thyrotoxicosis in a Cardiac Patient: A Case Report

## TL;DR

A 58-year-old cardiac patient with amiodarone-induced thyrotoxicosis was successfully treated with surgery after medical therapy failed.

## Contribution

Demonstrates the effectiveness of total thyroidectomy in managing refractory AIT in high-risk cardiac patients.

## Key findings

- Medical therapy failed to control thyrotoxicosis in a cardiac patient.
- Total thyroidectomy led to clinical stabilization in a refractory AIT case.
- Multidisciplinary input is crucial for managing high-risk AIT patients.

## Abstract

Amiodarone-induced thyrotoxicosis (AIT) presents a significant therapeutic challenge, particularly in patients with underlying cardiac comorbidities. We present a 58-year-old man with a background history of ischemic heart disease and atrial fibrillation who developed AIT following long-term amiodarone use. Despite the escalation of medical therapy, he remained clinically and biochemically thyrotoxic with symptomatic atrial fibrillation. Definitive management via total thyroidectomy was performed, resulting in clinical stabilization. This case highlights the importance of early multidisciplinary input and the role of total thyroidectomy in managing refractory AIT in high-risk cardiac patients.