# A case of hereditary alpha tryptasemia and presumptive eosinophilic granulomatosis with polyangiitis

## TL;DR

This case explores the connection between two rare conditions and shows that mepolizumab may help treat both.

## Contribution

The paper presents a novel treatment approach using mepolizumab for overlapping rare disorders.

## Key findings

- Mepolizumab was successfully used for eosinophilic granulomatosis with polyangiitis.
- The treatment may also benefit patients with hereditary alpha tryptasemia.
- This case highlights a potential overlap between two rare conditions.

## Abstract

This case is notable for the potential overlap of hereditary alpha tryptasemia and eosinophilic granulomatosis with polyangiitis. The successful use of mepolizumab, initially for eosinophilic granulomatosis with polyangiitis but potentially benefiting the patient's hereditary alpha tryptasemia, offers a novel approach to managing complex cases involving both rare disorders.