# An Insidious Source of Chronic Sinusitis and Recurrent Epistaxis: A Rare Case of Skull Base Glomangiopericytoma

**Authors:** Ismail Ozgenc, Alper Ozdilek, Mehmet Ozgenc, Demet Etit, Nazim Korkut

PMC · DOI: 10.7759/cureus.83348 · Cureus · 2025-05-02

## TL;DR

A rare tumor in the skull base was misdiagnosed as chronic sinusitis, highlighting the need for better awareness of this condition.

## Contribution

This case report highlights the diagnostic challenges of glomangiopericytoma and its similarity to chronic rhinosinusitis.

## Key findings

- GLC can mimic chronic rhinosinusitis, leading to delayed diagnosis.
- Endoscopic endonasal resection confirmed the presence of a rare skull base GLC.
- The tumor's malignant nature can cause irreversible damage if not promptly treated.

## Abstract

Glomangiopericytoma (GLC) is a rare malignant tumor of the sinonasal cavity that can lead to a variety of non-specific symptoms and consequently cause inaccurate diagnosis and delayed management. This can ultimately cause irreversible damage to the quality of life and result in a poor prognosis. We present the case of a 55-year-old male patient who suffered from the symptoms of chronic rhinosinusitis, anosmia, and multiple episodes of epistaxis with an endoscopic finding of a right-sided polyp-like mass within the sinonasal cavity. Further imaging studies revealed a mass originating from the skull base and a right-sided sphenoid sinus mucocele. Endoscopic endonasal resection and histopathological analysis confirmed a rare skull base GLC. The objective of this case report is to emphasize the diagnostic challenge of GLC due to its rare occurrence and bring awareness to its insidious and malignant nature that hides behind long-term sinonasal symptoms, mimicking chronic rhinosinusitis.

## Linked entities

- **Diseases:** chronic rhinosinusitis (MONDO:0006031), chronic sinusitis (MONDO:0006031)

## Full-text entities

- **Diseases:** sphenoid sinus mucocele (MESH:D009078), anosmia (MESH:D000857), tumor (MESH:D009369), Epistaxis (MESH:D004844), rhinosinusitis (MESH:D000092562), Chronic Sinusitis (MESH:D012852)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12126963/full.md

## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12126963/full.md

## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12126963/full.md

---
Source: https://tomesphere.com/paper/PMC12126963