# Extranodal Manifestation of Chronic Lymphocytic Leukemia: A Case of Bilateral Breast Involvement

**Authors:** Ensiyeh Bahadoran, Freidoon Solhjoo, Fatemeh SamieeRad

PMC · DOI: 10.1002/ccr3.70559 · Clinical Case Reports · 2025-05-30

## TL;DR

A rare case of chronic lymphocytic leukemia affecting both breasts is reported, highlighting its unusual extranodal presentation.

## Contribution

This case report presents a rare bilateral breast manifestation of chronic lymphocytic leukemia.

## Key findings

- Mammography identified large, lobulated masses in both breasts.
- Histopathology confirmed chronic lymphocytic leukemia involvement in the breast tissue.
- The case highlights the importance of considering CLL in breast mass evaluations.

## Abstract

Mammography revealed a large, lobulated, hyperdense mass in the right breast occupying nearly the entire breast and axillary region. A smaller but similar lobulated mass was present in the upper outer quadrant of the left breast. BIRADS 4 classification was assigned to both breasts, indicating suspicious findings requiring further evaluation. Based on histopathologic evaluation, it was found that the breast was involved by chronic lymphocytic leukemia.

## Linked entities

- **Diseases:** chronic lymphocytic leukemia (MONDO:0004948)

## Full-text entities

- **Diseases:** Chronic Lymphocytic Leukemia (MESH:D015451)

## Full text

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## Figures

6 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12124988/full.md

## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12124988/full.md

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Source: https://tomesphere.com/paper/PMC12124988