# Systemic Lupus Erythematosus Mimicking a Possible Eating Disorder

**Authors:** Landon Bruich, Dustin Williford, Jacob Filipek

PMC · DOI: 10.7759/cureus.83248 · Cureus · 2025-04-30

## TL;DR

A teenage girl's symptoms initially suggested an eating disorder but were later found to be caused by systemic lupus erythematosus.

## Contribution

Highlights a rare case where SLE presented with symptoms resembling an eating disorder.

## Key findings

- The patient's initial symptoms included weight loss and weakness, resembling anorexia nervosa.
- Diagnosis of SLE was confirmed after further investigation, despite the absence of classic lupus symptoms at first.
- Classic lupus findings appeared months after the disease onset.

## Abstract

Systemic lupus erythematosus (SLE) is an autoimmune disease that presents with a wide range of symptoms due to its ability to affect multiple organ systems. We present a case report of a 17-year-old female with a chief complaint of a four-month history of weight loss and generalized weakness, along with a two-month history of intermittent hematochezia. Features of the patient’s initial presentation made the treatment team suspicious of anorexia nervosa. However, further workup led the team to a diagnosis of SLE. This case exemplifies a rare presentation of lupus that initially mimicked an eating disorder and did not develop classic lupus findings until months after the disease process began.

## Linked entities

- **Diseases:** Systemic lupus erythematosus (MONDO:0007915), anorexia nervosa (MONDO:0005351)

## Full-text entities

- **Diseases:** Eating Disorder (MESH:D001068), autoimmune disease (MESH:D001327), weakness (MESH:D018908), anorexia nervosa (MESH:D000856), hematochezia (MESH:D006471), weight loss (MESH:D015431), SLE (MESH:D008180)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12124158/full.md

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Source: https://tomesphere.com/paper/PMC12124158