# A One Health Approach to Investigating Cache Valley Virus, Arkansas, USA, July 2023 **Authors:** Ann Carpenter, Noah Kojima, Theresa M. Dulski, Amanda E. Calvert, Kristen L. Burkhalter, Jennifer R. Ballard, Keith Blount, Anna Fagre, Elisa Thrasher, Katelyn Lazenby, Stephen Hedges, Audrey Long, Kerri Miazgowicz, Erin Wood, Phillip Owens, C. Roxanne Connelly, Carolyn V. Gould, J. Erin Staples, Laura Rothfeldt, Stacey W. Martin, Joan Burke PMC · DOI: 10.3201/eid3106.250052 · Emerging Infectious Diseases · 2025-06-01 ## TL;DR This paper investigates the effects of Cache Valley Virus in Arkansas using a One Health approach after detecting the virus in an aborted lamb. ## Contribution The study applies a One Health approach to investigate CVV's impact in Arkansas, where the virus had not been previously documented. ## Key findings - CVV RNA was detected in an aborted lamb from a flock in Arkansas in July 2023. - The investigation aimed to explore the potential effects of CVV on both human and animal health in the region. ## Abstract Cache Valley virus (CVV), a mosquitoborne virus, can cause neuroinvasive disease in humans and adverse reproductive outcomes in sheep and goats. In 2023, CVV RNA was detected in an aborted lamb from a flock in Arkansas, USA. We conducted a One Health investigation to explore the potential effects of CVV in Arkansas. ## Linked entities - **Species:** Homo sapiens (taxon 9606) ## Full-text entities - **Diseases:** neuroinvasive disease (MESH:D004194) - **Species:** Ovis aries (domestic sheep, species) [taxon 9940], Ollusvirus culvertonense (species) [taxon 2845707], Cache Valley virus (no rank) [taxon 80935], Homo sapiens (human, species) [taxon 9606], Capra hircus (domestic goat, species) [taxon 9925] ## Full text _Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12123922/full.md ## Figures 1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12123922/full.md ## References 15 references — full list in the complete paper: https://tomesphere.com/paper/PMC12123922/full.md --- Source: https://tomesphere.com/paper/PMC12123922