# The Efficiency of Systemic Dapsone in the Treatment of Acne Fulminans: A Clinical Case Report

## TL;DR

This paper reports a successful treatment of severe acne with dapsone in a patient unresponsive to other therapies.

## Contribution

Demonstrates the long-term efficacy of systemic dapsone in treating acne fulminans resistant to conventional treatments.

## Key findings

- Dapsone treatment at 100 mg/day resolved acne fulminans in a 31-year-old patient.
- No side effects or recurrences were observed after three years of follow-up.

## Abstract

Acne is a benign, complex, multifactorial disease resulting from hormonal, genetic, and environmental factors. It is considered a pubertal phenomenon and mainly affects adolescents, although some atypical cases can be observed in newborns and adults. Diagnosis is often straightforward, but in some cases, management can be difficult, with dramatic psychological and social consequences. Due to its antibiotic and immunomodulatory effects, dapsone has become an indispensable treatment in dermatology, particularly for severe acne resistant to conventional therapies. We report the case of a 31-year-old patient with acne fulminans, resistant to oral corticosteroids and isotretinoin, who was treated with 100 mg/day of dapsone, resulting in complete resolution of acne after six months of treatment. No side effects or recurrences were observed after three years of semi-annual follow-up.