# The Prevalence and Determinants of Long-Term Glycemic Control Based on Serial Glycosylated Haemoglobin Values in Type 2 Diabetes Mellitus

**Authors:** Maya Tholiya, Mahadev Meena, Rajnish Joshi, Shubham Atal, Ankur Joshi, Mohit Awasthi, Yasmee Khan

PMC · DOI: 10.7759/cureus.83221 · Cureus · 2025-04-29

## TL;DR

This study explores factors affecting long-term blood sugar control in people with type 2 diabetes in India.

## Contribution

The study identifies demographic, clinical, and therapeutic factors influencing glycemic control in T2DM patients.

## Key findings

- Age, gender, and obesity significantly impact glycemic control.
- Medication adherence and comorbidities influence long-term outcomes.
- Personalized treatment and lifestyle changes are crucial for managing T2DM.

## Abstract

Introduction: Diabetes mellitus has become a significant public health issue in India, with a considerable proportion of the population living with the condition. Type 2 Diabetes Mellitus (T2DM), commonly linked with obesity, is associated with metabolic abnormalities and vascular complications. Effective long-term glycemic control is important in preventing complications and improving patient outcomes.

Objective: To examine associations between demographic, anthropometric, clinical, and therapeutic characteristics and long-term glycemic control status in individuals with T2DM in 314 participants.

Methodology and results: This is a longitudinal study conducted to evaluate factors such as demographic characteristics, clinical parameters, duration of T2DM, medication use, and comorbidities. Findings highlight the impact of age, gender, obesity, medication adherence, and comorbid conditions on glycemic control.

Conclusion: A multi-faceted approach, including lifestyle modifications, personalized treatment plans, and patient education, is essential for achieving optimal glycemic outcomes in T2DM management. ​

## Linked entities

- **Diseases:** Type 2 Diabetes Mellitus (MONDO:0005148), T2DM (MONDO:0005148)

## Full-text entities

- **Diseases:** Diabetes mellitus (MESH:D003920), T2DM (MESH:D003924), obesity (MESH:D009765)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12122831/full.md

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Source: https://tomesphere.com/paper/PMC12122831