# Population-based estimates of different dosage types of psychedelic use across socio-demographic groups in Germany

**Authors:** Sebastian Sattler, Suzanne Wood, Margit Anne Petersen, Fiona Seiffert, Guido Mehlkop

PMC · DOI: 10.1038/s41598-025-03873-0 · Scientific Reports · 2025-05-29

## TL;DR

This study estimates psychedelic use patterns in Germany, showing limited use and variation across different demographic groups.

## Contribution

The study provides population-based estimates of psychedelic use by dosage type and socio-demographic factors in Germany.

## Key findings

- Only 0.7% of respondents reported past six-month psychedelic use.
- Medium to high dosing was more common than microdosing.
- Psychedelic use varied by gender, age, income, and location.

## Abstract

Psychedelic drugs, particularly taking small amounts of psychedelics in a cyclical pattern over days (so-called microdosing), have garnered growing scientific and public interest, but representative data on different dosage levels is scarce. To better understand this trend, we surveyed a nationwide sample of 11,299 adults in Germany. The survey assessed lifetime and past six-month psychedelic use by dosage as well as socio-demographic variables (sex, age, education, employment status, household equivalence income, partner arrangements, and place of residence). Results show that 5.0% of respondents self-reported lifetime psychedelic use, while 0.7% reported past six-month use. Medium to high dosing was more prevalent than microdosing. Moreover, high probabilities of using multiple forms of psychedelics were uncovered. We also observed variation in use across socio-demographic groups. For example, psychedelics use was less likely in females than males, and older than younger respondents. Past six-month microdosing was less likely in rural areas, and past six-month medium to high dosing was less prevalent in individuals with higher income or who live with a partner. This study shows limited support for widespread use in Germany and highlights diverse usage patterns across socio-demographics. These findings can inform policies, especially considering the overlap in usage of various substances.

The online version contains supplementary material available at 10.1038/s41598-025-03873-0.

## Full-text entities

- **Genes:** HTR2A (5-hydroxytryptamine receptor 2A) [NCBI Gene 3356] {aka 5-HT2A, HTR2}
- **Diseases:** anxiety (MESH:D001007), cardiovascular effects (MESH:D002318), hypertension (MESH:D006973), criminal or antisocial behavior (MESH:D000987), seizures (MESH:D012640), overdose (MESH:D062787), post-traumatic stress disorder (MESH:D013313), hypothermia (MESH:D007035), depression (MESH:D003866), paranoia (MESH:D010259), dissociation (MESH:D004213), death (MESH:D003643), COVID pandemic (MESH:D000086382), dizziness (MESH:D004244), psychosis (MESH:D011618), addiction (MESH:D019966), panic (MESH:D016584), hyperthermia (MESH:D005334), hallucinations (MESH:D006212), arrhythmia (MESH:D001145), cardiorespiratory problems (MESH:D019973), nausea (MESH:D009325)
- **Chemicals:** THC (MESH:D013759), ibogaine (MESH:D007050), serotonin (MESH:D012701), esketamine (MESH:C000629870), alcohol (MESH:D000438), mescaline (MESH:D008635), 3,4-Methylenedioxy methamphetamine (MESH:D018817), dopamine (MESH:D004298), Psilocybin (MESH:D011562), LSD (MESH:D008238), 1P-LSD (-), DMT (MESH:D004130)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12122786/full.md

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Source: https://tomesphere.com/paper/PMC12122786