# Case Report: Extensive deep vein thrombosis and venous pseudoaneurysm following percutaneous transcatheter tricuspid valve intervention

**Authors:** Zaid Abood, M. Fuad Jan, Eric S. Weiss, Tanvir Bajwa, Suhail Q. Allaqaband, Mark W. Mewissen

PMC · DOI: 10.3389/fcvm.2025.1568102 · Frontiers in Cardiovascular Medicine · 2025-05-16

## TL;DR

A patient developed severe venous complications after a minimally invasive heart valve procedure, highlighting the need for close monitoring.

## Contribution

This case report highlights venous access site complications following TTVI, a previously under-recognized risk.

## Key findings

- Phlegmasia cerulea dolens occurred after TTVI via a large sheath in the femoral vein.
- Venous thrombosis and pseudoaneurysm were identified and successfully treated with endovascular intervention.
- Post-procedure surveillance is crucial to detect and manage venous access site complications.

## Abstract

Transcatheter tricuspid valve intervention (TTVI) has evolved as a less-invasive alternative to surgical treatment of severe tricuspid regurgitation. Although venously delivered valves have been introduced, the risk of venous access site complications is unknown. We present a patient who suffered phlegmasia cerulea dolens post-TTVI.

We present an 88-year-old female patient who developed phlegmasia cerulea dolens of the right lower extremity shortly after successful TTVI delivered through the right common femoral vein via a 35F sheath. Ipsilateral transpopliteal venography demonstrated an occlusive thrombus in the right common femoral vein and the incidental finding of an external iliac vein pseudoaneurysm. Endovascular treatment consisting of mechanical thrombectomy followed by adjunctive placement of self-expanding metallic stents resulted in restoration of iliofemoral venous outflow and excellent recovery with resolution of the patient's symptoms.

Surveillance, e.g., duplex ultrasonography, immediately post-TTVI is important to rule out acute thrombosis of the venous access site and other complications associated with a large sheath.

## Linked entities

- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** vein thrombosis (MESH:D012170), thrombosis (MESH:D013927), venous pseudoaneurysm (MESH:D017541), phlegmasia cerulea dolens (MESH:D013924), tricuspid regurgitation (MESH:D014262), external iliac vein pseudoaneurysm (MESH:D062108)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12122495/full.md

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Source: https://tomesphere.com/paper/PMC12122495