# Case report and literature review: endoscopic extended endonasal resection of two cases of giant chondroma

## TL;DR

This case report describes the successful endoscopic removal of two rare giant skull base chondromas, emphasizing the importance of complete resection for better outcomes.

## Contribution

The paper contributes two new clinical cases of giant chondromas treated with endoscopic extended endonasal resection, highlighting the effectiveness of this approach.

## Key findings

- Endoscopic extended endonasal resection achieved near-total removal of two giant skull base chondromas.
- Complete resection improved patient recovery and may reduce tumor recurrence.
- Postoperative histopathology confirmed the diagnosis of chondroma in both cases.

## Abstract

Intracranial chondromas are exceedingly rare neoplasms, accounting for 0.2% to 0.3% of all intracranial tumors. These tumors predominantly originate from the skull base, particularly at the cartilaginous junctions of the cranial sutures, with the sella turcica being the most common site.

Between April 2022 and August 2023, the Department of Neurosurgery at Xingtai People’s Hospital Affiliated to Hebei Medical University treated two cases of giant skull base chondromas using endoscopic extended endonasal resection. Near-total resection was achieved, and postoperative histopathological examination confirmed the diagnosis of chondroma. Both patients recovered well postoperatively.

Skull base chondromas are deeply seated and often involve extensive regions. Complete surgical resection remains the greatest challenge and the most critical factor influencing prognosis.selecting the appropriate surgical approach and achieving complete endoscopic resection can effectively prevent tumor recurrence and improve patient quality of life.