# Evaluation of functional capacity and risk of depression in older patients with cancer as part of the comprehensive geriatric assessment

**Authors:** Wiesław Fidecki, Katarzyna Przylepa, Marek Wytrzyszczewski, Mariusz Wysokiński

PMC · DOI: 10.3389/fnagi.2025.1595336 · Frontiers in Aging Neuroscience · 2025-05-16

## TL;DR

This study examines how functional capacity affects depression risk in older cancer patients using standardized assessments.

## Contribution

The paper introduces a regression model linking functional capacity scores to depression symptoms in elderly cancer patients.

## Key findings

- Most patients were fully functional, but many showed depression symptoms.
- Functional capacity, especially memory and daily activities, significantly correlates with depression risk.
- Over 30% of elderly cancer patients exhibited symptoms of depression.

## Abstract

The patient’s somatic health status plays an important role in the factors predisposing to the development of depression. Any disease, especially a chronic one, often associated with pain, may contribute to the development of depression. The aim of the study was to assess the impact of functional capacity on the occurrence of depression among elderly cancer patients.

The work used the diagnostic survey method and survey technique research tool consisted of standardized questionnaires: the Nurses’ Observation Scale for Geriatric Patients (NOSGER), the Barthel scale, and the Geriatric Depression Scale (GDS). The authors conducted the study among 110 older adults patients with hospitalized at the Lublin Region Oncology Center in 2022.

When assessing patients using the NOSGER scale, the average result for the entire group was 45.98 ± 12.58 points. The examined people functioned best in terms of memory - average of 5.99 ± 1.32 points. The worst functioning was in the instrumental activities of everyday life - average 9.16 ± 3.61 points. In the assessment of the functional status using the Barthel scale, 54.54% of the respondents were classified as light. Based on the assessment of patients using the GDS scale, it was found that as many as 66.36% of the respondents did not experience symptoms of depression. The regression model showed that the NOSGER scale was a statistically significant variable explaining the geriatric depression scale score in the study group (p < 0.001).

Most respondents were fully functional. The surveyed seniors suffering from cancer had the greatest difficulties in the areas of moods and emotions as well as instrumental activities of everyday life. The occurrence of depression symptoms was found in over 30.00% of respondents. It is advisable to use research tools that take into account a wider range of aspects when assessing the impact of functional capacity on the possibility of depression among geriatric patients with cancer.

## Linked entities

- **Diseases:** cancer (MONDO:0004992)

## Full-text entities

- **Diseases:** pain (MESH:D010146), cancer (MESH:D009369), Geriatric Depression (MESH:D003866)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

50 references — full list in the complete paper: https://tomesphere.com/paper/PMC12122436/full.md

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Source: https://tomesphere.com/paper/PMC12122436