# Perianal panniculitis presenting as chronic perianal pain: a diagnostic challenge

**Authors:** Imran Thariq Ajmal, Amrithraj Thiyagarajan, Felix Anand Raj, Santhya Govindaraju, P Pravali, Venkiteswaran Muralidhar

PMC · DOI: 10.1093/jscr/rjaf340 · Journal of Surgical Case Reports · 2025-05-30

## TL;DR

This paper discusses a rare condition called perianal panniculitis that causes chronic perianal pain and highlights the challenges in diagnosing it correctly.

## Contribution

The paper emphasizes the importance of recognizing perianal panniculitis in differential diagnosis to prevent misdiagnosis.

## Key findings

- Perianal panniculitis is a rare condition that can resemble other perianal diseases.
- There is limited literature on diagnosing and managing perianal panniculitis.
- Early diagnosis is crucial to avoid mismanagement and ensure proper treatment.

## Abstract

Perianal panniculitis is a rare inflammatory condition characterized by painful, tender, and swollen lesions in the perianal region. It can mimic other conditions such as abscesses, fistulas, malignancies, or inflammatory bowel disease. This case reflects on the rarity of Perianal panniculitis and its varied presentations and the importance of considering it in the differential diagnosis of perianal lesions. Furthermore, the case highlights limited literature addressing tools of diagnosis, management, and protocol for long-term follow-up to ensure early identification and appropriate management in case of recurrence. Considering perianal panniculitis in the differential diagnosis is crucial to avoid misdiagnosis and ensure timely treatment.

## Linked entities

- **Diseases:** inflammatory bowel disease (MONDO:0005265)

## Full-text entities

- **Diseases:** abscesses (MESH:D000038), fistulas (MESH:D005402), Perianal panniculitis (MESH:D015434), malignancies (MESH:D009369), inflammatory (MESH:D007249), perianal pain (MESH:D010146), perianal lesions (MESH:D000694), inflammatory bowel disease (MESH:D015212)

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12122281/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12122281/full.md

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Source: https://tomesphere.com/paper/PMC12122281