# Perioperative Anticoagulation and Risk Assessment: Building a Bridge Over a STREAM

**Authors:** Anil Harrison, Sushil Rayamajhi

PMC · DOI: 10.31729/jnma.8910 · JNMA: Journal of the Nepal Medical Association · 2025-03-31

## TL;DR

This paper introduces a mnemonic called STREAM to help doctors decide when to use bridging anticoagulation during surgery, reducing risks of bleeding and blood clots.

## Contribution

The novel contribution is the STREAM mnemonic, which simplifies decision-making for perioperative anticoagulation bridging.

## Key findings

- STREAM highlights high-risk scenarios requiring bridging anticoagulation.
- The mnemonic includes recent stroke, severe thrombophilia, and mechanical heart valves.
- STREAM aims to optimize anticoagulation while minimizing bleeding and clot risks.

## Abstract

Perioperative care requires a comprehensive assessment of the risks of bleeding and thrombosis. The 2022 CHEST Guidelines offer an empirical foundation for customized treatment using clinical judgment and risk assessment based on CHA2DS2-VASC and HAS-BLED scores. Despite the ease of access to anticoagulation guidelines, decision-making remains challenging, particularly when determining the necessity of bridging therapy with unfractionated or low-molecular-weight heparin. To facilitate this decision, we provide a mnemonic, STREAM, that highlights high-risk situations that require bridging. These include recent stroke or transient ischemic attack, severe thrombophilia, rheumatic valvular disease, recent venous thromboembolism, atrial fibrillation with high CHA2DS2-VASC scores, and mechanical heart valves. This mnemonic offers physicians a methodical approach to optimize perioperative anticoagulation control while minimizing the risk of hemorrhage and thrombosis.

## Linked entities

- **Diseases:** stroke (MONDO:0005098), transient ischemic attack (MONDO:0005264), thrombophilia (MONDO:0002305), venous thromboembolism (MONDO:0005399), atrial fibrillation (MONDO:0004981)

## Full-text entities

- **Diseases:** bleeding (MESH:D006470), transient ischemic attack (MESH:D002546), thrombophilia (MESH:D019851), venous thromboembolism (MESH:D054556), rheumatic valvular disease (MESH:D012216), thrombosis (MESH:D013927), atrial fibrillation (MESH:D001281), stroke (MESH:D020521)
- **Chemicals:** heparin (MESH:D006493)

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12122276/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12122276/full.md

---
Source: https://tomesphere.com/paper/PMC12122276