# Postpartum Cavernous Sinus Thrombosis Associated with Eclampsia and Gestational Diabetes Mellitus: A Case Report

**Authors:** Shasank Chitrakar, Saroj Babu Aryal, Tirtha Man Shrestha

PMC · DOI: 10.31729/jnma.8904 · JNMA: Journal of the Nepal Medical Association · 2025-03-31

## TL;DR

This case report describes a rare instance of postpartum cavernous sinus thrombosis in a woman with eclampsia and gestational diabetes, highlighting its clinical presentation and treatment.

## Contribution

The novelty lies in documenting a rare thrombotic complication in the context of eclampsia and gestational diabetes.

## Key findings

- The patient presented with postpartum headache and was diagnosed with cavernous sinus thrombosis via MRV.
- Treatment with heparin and antibiotics led to recovery, followed by discharge on oral rivaroxaban.
- The case underscores the heightened thrombosis risk during pregnancy's hypercoagulable state.

## Abstract

Pregnancy is the pro-thrombotic state. The objective of this report is to highlight the rare occurance of postpartum cavernous sinus thrombosis associated with eclampsia and gestational diabetes mellitus, emphasizing its clinical presentation. A 25-year-old Muslim female came with the complaint of headache,post auricular and right parietal region on 8th day post-partum. She had a history of postpartum eclampsia and Gestational Diabetes Mellitus for which she was treated with magnesium sulfate and oral hypoglycaemic agents respectively. MRV showed a filling defect in right transverse sinus, sigmoid sinus, and internal jugular vein. She was then admitted to the ward and was treated with heparin and antibiotics. She was then discharged on oral rivaroxaban. As pregnancy is itself a state of hyper-coagulable state, there seems to be a significant thrombosis risk. Hence clinicians should be aware of the possible thrombotic disorder in the background of this vignette.

## Linked entities

- **Chemicals:** magnesium sulfate (PubChem CID 24083), rivaroxaban (PubChem CID 6433119)
- **Diseases:** eclampsia (MONDO:0001754), gestational diabetes mellitus (MONDO:0005406), cavernous sinus thrombosis (MONDO:0002694)

## Full-text entities

- **Diseases:** Eclampsia (MESH:D004461), Cavernous Sinus Thrombosis (MESH:D020226), Gestational Diabetes Mellitus (MESH:D016640), thrombosis (MESH:D013927), headache (MESH:D006261)
- **Chemicals:** magnesium sulfate (MESH:D008278), rivaroxaban (MESH:D000069552), heparin (MESH:D006493)

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12122268/full.md

## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12122268/full.md

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Source: https://tomesphere.com/paper/PMC12122268