# Late Periprosthetic Joint Infection After a Total Hip Arthroplasty Caused by Peptoniphilus Species: A Case Report and Literature Review

## TL;DR

A 65-year-old woman had a late hip infection caused by Peptoniphilus species, treated with two-stage surgery and specific antibiotics.

## Contribution

Highlights Peptoniphilus species as a causative agent in late joint infections and recommends treatment strategies.

## Key findings

- Peptoniphilus species can cause late periprosthetic joint infections.
- Two-stage revision surgery is effective for treating such infections.
- Clindamycin and cephalosporins are recommended for postoperative antibiotic therapy.

## Abstract

In this report, we present the clinical course of a 65-year-old woman who underwent a two-stage revision total hip arthroplasty (THA) for a late periprosthetic joint infection (PJI) caused by Peptoniphilus species (Peptoniphilus sp.). Furthermore, we conducted a literature review to contribute to the growing body of evidence regarding PJI caused by Peptoniphilus sp. Recognizing Peptoniphilus sp. as a potential causative pathogen in late PJI is important. Treatment should involve a two-stage revision surgery, with clindamycin (CLDM) and cephalosporins recommended for postoperative antibiotic therapy.