# Structure of Trials Assessing Endovascular Embolization for Brain Arteriovenous Malformations: A Scoping Review

## TL;DR

This scoping review examines the design and outcomes of trials on endovascular embolization for brain AVMs to identify common endpoints and guide future research.

## Contribution

The paper synthesizes common endpoints and design elements in AVM embolization trials to inform future research directions.

## Key findings

- Trials on endovascular embolization for AVMs show heterogeneous reporting of outcomes and design elements.
- Common endpoints include safety and efficacy measures, with a need for standardized reporting.
- Future trials should adapt to the rapid advancements in endovascular technologies.

## Abstract

Recent advancements in embolic agents and endovascular techniques have led to increased interest in exploring endovascular embolization as a viable treatment for brain arteriovenous malformations. Several trials have investigated the use of various embolic agents for the treatment of arteriovenous malformations (AVMs) endovascularly. However, the reporting outcomes and design elements in these studies are heterogeneous and include inclusion/exclusion criteria and evaluated endpoints. This scoping review synthesized common endpoints cited within embolic endovascular AVM trials for monitoring their safety and efficacy, with a commentary on common threads of focus in future trials for evaluating AVM treatment, including adapting designs to be on par with the pace of advancements in endovascular technologies.