# Is uterine artery embolisation a safe and effective modality to treat submucosal fibroids?

**Authors:** Rayhab Mashal, Neeral Patel, Bhavna Pitrola, Thomas Sewell, Asmaa Al-Kufaishi, Shabnam Taheri, Mohamad Hamady

PMC · DOI: 10.1186/s42155-025-00546-x · CVIR Endovascular · 2025-05-28

## TL;DR

Uterine artery embolisation effectively reduces submucosal fibroids with high patient satisfaction and low severe side effects.

## Contribution

Demonstrates UFE's efficacy in reducing submucosal fibroid volume and its safety profile with minimal severe adverse events.

## Key findings

- UFE reduced submucosal fibroid volume by 64% and achieved over 90% devascularization in 94.8% of cases.
- 84.5% of patients were discharged without further intervention, indicating high patient satisfaction.
- Severe adverse events occurred in only 3.2% of patients, with pelvic infections being the most significant.

## Abstract

• Uterine fibroid embolization (UFE) reduced the median volume of dominant submucosal leiomyomas by 64% and achieved over 90% devascularization in 94.8% of cases.

• High patient satisfaction was observed, with 84.5% of patients successfully discharged without needing further intervention.

• Severe adverse events were rare, affecting only 3.2% of patients, with pelvic infections being the most significant.

• Mild adverse events occurred in 16.8% of patients, including infections requiring antibiotics and persistent vaginal discharge.

• A multidisciplinary approach is essential for managing patients with submucosal leiomyomas undergoing UFE to ensure optimal treatment outcomes.

## Full-text entities

- **Diseases:** infections (MESH:D007239), pelvic infections (MESH:D034161), fibroids (MESH:D007889)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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Source: https://tomesphere.com/paper/PMC12120088