This paper is marked retracted in the scholarly record (OpenAlex). Interpret its findings with caution.
Retraction Note: Glyoxalase I inhibition induces apoptosis in irradiated MCF-7 cells via a novel mechanism involving Hsp27, p53 and NF-κB
C Antognelli, I Palumbo, C Aristei, V N Talesa
Abstract
Genes, proteins, chemicals, diseases, species, mutations and cell lines named across the full text — each resolved to its canonical identifier and authoritative record.
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Taxonomy
TopicsAdvanced Glycation End Products research
Retraction to: British Journal of Cancer 10.1038/bjc.2014.280, published online 10 June 2014
The Editor-in-Chief has retracted this article. After publication, concerns were raised regarding similarities in the western blot images presented in the Figures. Specifically:
- The western blots in Figs. 2b, 2d and 4e appear to contain duplicate bands.
- The cytosol β-actin and Bcl-XL blots in Fig. 5a appear highly similar to cytosol β-actin and Cyt c (rotated 180 degrees) in Fig. 5b (left).
- In Fig. 5b (right) and c, the mitochondria β-actin bands appear highly similar.
- The blots presented in Fig. 6d (left) appear highly similar to those in Fig. 6e (left).
The authors have stated that the blots are similar, but not identical. However, they have been unable to provide the raw data to support this statement. Due to the high number of potential issues, the Editor-in-Chief no longer has confidence in the presented data.
V N Talesa has stated on behalf of all authors that they disagree with this retraction.