# Spesolimab in generalized pustular psoriasis complicated by acrodermatitis continua of Hallopeau: a case report and mechanistic insights

## TL;DR

A 62-year-old woman with severe skin conditions improved significantly after treatment with spesolimab, with no adverse effects.

## Contribution

This case report demonstrates the effectiveness of spesolimab in treating generalized pustular psoriasis complicated by ACH.

## Key findings

- Spesolimab treatment led to significant improvement in the patient's GPP and ACH.
- No adverse reactions were observed during follow-up after spesolimab administration.

## Abstract

A 62-year-old Chinese woman presented to the hospital for help with generalized pustular psoriasis (GPP) and acrodermatitis continua of Hallopeau (ACH). While conventional treatments failed to achieve significant improvement, the patient received two doses of spesolimab, and the effect was remarkable. No adverse reactions were observed in the follow-up period.