# Management of Multidrug-Resistant Acinetobacter Infection Following Open Reduction and Internal Fixation of a Right Acetabular Fracture: A Case Report

**Authors:** Rajeev P Nagassar, Darian Singh, Raakesh Goalan

PMC · DOI: 10.7759/cureus.83125 · Cureus · 2025-04-28

## TL;DR

This case report describes the successful treatment of a multidrug-resistant Acinetobacter infection after a hip fracture surgery.

## Contribution

The report presents a novel case of managing MDR Acinetobacter infection using culture-guided antibiotics and local therapy in orthopedic surgery.

## Key findings

- MDR Acinetobacter infection was successfully treated with culture-guided antibiotic selection.
- Local antibiotic therapy played a supportive role in managing the deep surgical site infection.
- Collaboration with microbiology teams is essential for treating MDR infections in orthopedic patients.

## Abstract

Postoperative infections with multidrug-resistant (MDR) Acinetobacter baumannii present significant challenges in orthopedic surgery. This case report highlights the management and successful treatment of an MDR Acinetobacter infection following open reduction and internal fixation (ORIF) of a right acetabulum fracture. A 51-year-old male presented with a comminuted right acetabular fracture following a motor vehicle accident. Initial ORIF was complicated by intraoperative blood loss, necessitating early termination of the procedure. The patient subsequently developed a deep surgical site infection caused by MDR A. baumannii, resistant to multiple antibiotic classes. This case underscores the importance of culture-guided antibiotic selection, a role for the use of local antibiotic therapy. It also highlights therapeutic challenges in managing MDR infections in orthopedic surgery and the need for collaboration with the microbiology team.

## Linked entities

- **Diseases:** Acinetobacter infection (MONDO:0006635)
- **Species:** Acinetobacter baumannii (taxon 470)

## Full-text entities

- **Diseases:** acetabulum fracture (MESH:D050723), Postoperative infections (MESH:D013530), blood loss (MESH:D016063), Acetabular Fracture (OMIM:142700), infection (MESH:D007239), Acinetobacter Infection (MESH:D000151)
- **Species:** Homo sapiens (human, species) [taxon 9606], Acinetobacter baumannii (species) [taxon 470]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12118315/full.md

## References

21 references — full list in the complete paper: https://tomesphere.com/paper/PMC12118315/full.md

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Source: https://tomesphere.com/paper/PMC12118315