# A case of Hyperkalemia-induced Brugada Phenocopy: a rare but serious electrocardiographic imposter

**Authors:** Abraam Rezkalla, Islam Rajab, Fathi Milhem, Moath Hattab, Yezin Shamoon, Fayez Shamoon

PMC · DOI: 10.1093/omcr/omaf036 · Oxford Medical Case Reports · 2025-05-28

## TL;DR

A woman's ECG showed a Brugada pattern due to high potassium levels, which normalized after treatment.

## Contribution

This case highlights hyperkalemia as a rare cause of a Brugada phenocopy, emphasizing the importance of electrolyte evaluation.

## Key findings

- Hyperkalemia can mimic Brugada Syndrome on ECG.
- ECG returned to normal after treating the underlying electrolyte imbalance.

## Abstract

Brugada Syndrome is a potentially fatal, hereditary cardiac disorder that may precipitate sudden cardiac death if not identified. An electrocardiogram (ECG) revealing a characteristic coved ST segment elevation followed by negative T wave in a right-sided precordial lead is pathognomonic for the Brugada pattern. Recently it has been shown that certain abnormalities, such as an electrolyte disturbance, may precipitate a Brugada pattern on ECG. Once the precipitating factor is treated, the rhythm reverts to baseline, coining the term Brugada Phenocopy. Here we present a captivating case of a 40-year-old female who was found unresponsive and determined to have a Brugada pattern on ECG secondary to hyperkalemia. Once appropriately treated, ECG reverts to normal baseline.

## Linked entities

- **Diseases:** Brugada Syndrome (MONDO:0015263)

## Full-text entities

- **Diseases:** hereditary cardiac disorder (MESH:D009386), imposter (MESH:C000711547), sudden cardiac death (MESH:D016757), Brugada (MESH:D053840), Hyperkalemia (MESH:D006947)

## Full text

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12118059/full.md

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Source: https://tomesphere.com/paper/PMC12118059