# A fatal case of cytomegalovirus pneumonia with coexisting aspergillus infection in a immunodeficient patient

## TL;DR

A woman with a weak immune system died from a rare combination of CMV and fungal pneumonia, highlighting the need for early diagnosis in similar cases.

## Contribution

The case highlights the rare and complex coinfection of CMV and aspergillus in a non-transplant immunodeficient patient.

## Key findings

- The patient had a fatal outcome despite treatment for CMV and fungal pneumonia.
- Coinfection in non-transplant immunocompromised patients is rare and challenging to manage.
- Early recognition and combination therapy may improve outcomes in such cases.

## Abstract

Introduction: Cytomegalovirus (CMV) disease is common among transplant patients, who are also prone to secondary bacterial or fungal infections. However, coinfection in immunodeficient patients is rare and often makes diagnosis and treatment challenging.

Patient concerns: The patient was an older woman with low immune function but was not a transplant patient.

Diagnosis: The patient presented with complaints of fever and shortness of breath for 1 day. After a medical evaluation, she was diagnosed with CMV infection and fungal pneumonia.

Interventions: The patient received ceftriaxone + human immunoglobulin + voriconazole treatment.

Outcome: The patient’s condition deteriorated and she eventually died of myocardial infarction.

Conclusion: For immunocompromised patients, early recognition of coinfections, along with combination medication, maybe a key factor in improving prognosis.