# A Rare Presentation of a Spinal Lesion: Immunoglobulin G4-Related Hypertrophic Spinal Pachymeningitis

## TL;DR

A 64-year-old man had a rare spinal condition caused by an IgG4-related inflammatory disease, showing the need to consider uncommon diagnoses for spinal lesions.

## Contribution

This case presents a rare instance of IgG4-related hypertrophic spinal pachymeningitis, emphasizing its diagnostic challenges.

## Key findings

- A spinal lesion in a 64-year-old man was diagnosed as IgG4-related hypertrophic spinal pachymeningitis.
- Histopathological confirmation was crucial for accurate diagnosis and treatment planning.
- The case underscores the importance of considering rare inflammatory diseases in spinal lesion differential diagnoses.

## Abstract

Immunoglobulin G4-related disease is a rare systemic condition that can affect multiple organs, though involvement of the central nervous system is uncommon. This report discusses an unusual case of a 64-year-old man who experienced neurological symptoms due to a spinal lesion. Imaging revealed a compressive mass at the cervical spine level, which was surgically removed and later confirmed to be IgG4-related hypertrophic spinal pachymeningitis. This case highlights the importance of considering rare inflammatory conditions in the differential diagnosis of spinal lesions and emphasizes the role of histopathological confirmation for accurate diagnosis and treatment planning.