# Diagnostic Tools Applied to Determine Thyroid Lipoadenoma: A Case Report

**Authors:** Luo-Wei Chan, Jia-Yu Chen, Jui-Ju Kao, Min-Wei Yu, Hsin-Rou Liang

PMC · DOI: 10.7759/cureus.83096 · Cureus · 2025-04-27

## TL;DR

This case report describes a rare thyroid tumor diagnosed through surgery after inconclusive imaging and biopsy results.

## Contribution

Highlights the diagnostic challenges of thyroid lipoadenoma and the need for surgical confirmation.

## Key findings

- Imaging and FNA failed to diagnose thyroid lipoadenoma in this case.
- Surgical removal confirmed the presence of a benign tumor with 40-50% adipose tissue.
- Thyroidectomy is often required for definitive diagnosis of this rare condition.

## Abstract

We report a case of thyroid lipoadenoma of the thyroid gland, an extremely rare benign lesion containing both adipose tissue and thyroid tissue. A 74-year-old Chinese female underwent a series of examinations for the incidental thyroid nodule. The sonogram showed a well-encapsulated and hyper-isoechoic nodule in the left thyroid gland. The CT revealed a low-attenuation thyroid nodule without evidence of extrathyroid extension. Fine-needle aspiration (FNA) cytology reported atypia of undetermined significance. As none of these studies could confirm the diagnosis and rule out potential malignancy, the patient ultimately received minimally invasive video-assisted thyroidectomy (MIVAT). Final pathology confirmed the diagnosis of thyroid lipoadenoma, consisting of adipose tissue and follicular cells, with adipose tissue comprising approximately 40% to 50% of the lesion. Common diagnostic tools for thyroid nodules offer limited utility in identifying thyroid lipoadenoma, often requiring thyroidectomy for definitive diagnosis and management.

## Linked entities

- **Species:** Homo sapiens (taxon 9606)

## Full-text entities

- **Diseases:** thyroid nodule (MESH:D016606), Thyroid Lipoadenoma (MESH:D013966), malignancy (MESH:D009369)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12116825/full.md

## References

6 references — full list in the complete paper: https://tomesphere.com/paper/PMC12116825/full.md

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Source: https://tomesphere.com/paper/PMC12116825