Author Correction: Tanshinone IIA affects the malignant growth of Cholangiocarcinoma cells by inhibiting the PI3K-Akt-mTOR pathway
Huayuan Liu, Caiyun Liu, Mengya Wang, Dongxu Sun, Pengcheng Zhu, Ping Zhang, Xueying Tan, Guangjun Shi
Abstract
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Taxonomy
TopicsGinger and Zingiberaceae research
Correction to: Scientific Reports 10.1038/s41598-021-98948-z, published online 29 September 2021
The original version of this Article contained errors in Figure 4, panels F and G, where the 0h image of the “Tan-IIA+740y-p” group was incorrectly used as the image of the “Tan-IIA group”. The original Fig. 4 and accompanying legend appear below.Fig. 4PI3K agonists attenuate the tumor suppressive effect of Tan-IIA. After the addition of 740y-p (10 µg/mL) to the system in which Tan-IIA (24 h IC50 concentration) and Cholangiocarcinoma cells were co-cultured, the tumor suppressive effect of Tan-IIA was attenuated. (A–E) The inhibitory effect of Tan-IIA on the proliferation of Cholangiocarcinoma cells decreased after the addition of 740y-p. (F–L) The ability of Tan-IIA to inhibit the invasion and migration of Cholangiocarcinoma cells was reduced after the addition of 740y-p. (M–O) The apoptosis-inducing effect of Tan-IIA on Cholangiocarcinoma cells was diminished after 740y-p was added. Compared with control, *p < 0.05; **p < 0.01; ***p < 0.001.
The original Article has been corrected.