# Silicosis in the Setting of Chronic Granite Exposure: A Case Report

**Authors:** Sylvia Li, Henrik Ghantarchyan, Sarkis Arabian

PMC · DOI: 10.7759/cureus.83095 · Cureus · 2025-04-27

## TL;DR

A man who worked in a granite factory for 18 years developed silicosis, a lung disease caused by inhaling silica dust.

## Contribution

This case report highlights silicosis in a worker with consistent mask use, emphasizing the disease's potential despite protective measures.

## Key findings

- The patient's symptoms and occupational history were consistent with silicosis.
- Infectious causes like tuberculosis and fungal infections were ruled out through testing.
- Radiographic findings supported the diagnosis of silicosis despite mask use.

## Abstract

Silicosis develops when inhaled silica particles reach the alveoli, causing interstitial lung disease. We present the case of a 50-year-old male with no known past medical history who arrived at the emergency department with a 10-month history of dyspnea, which had worsened over the past four days. He reported working in a granite factory for 18 years, consistently wearing a mask while cutting and grinding stone. Initial laboratory tests were unremarkable. A viral respiratory panel and acid-fast bacilli cultures and smears (repeated three times) were all negative, lowering the suspicion for tuberculosis. Antifungal testing was also negative, except for a positive Histoplasma antibody; however, the urine Histoplasma antigen was negative. Bronchoalveolar lavage revealed an unremarkable cell differential, and respiratory cultures were negative. Given the negative infectious workup, along with the radiographic findings and occupational history, the patient’s presentation was most consistent with silicosis.

## Linked entities

- **Chemicals:** silica (PubChem CID 24261)
- **Diseases:** silicosis (MONDO:0005960), tuberculosis (MONDO:0018076)

## Full-text entities

- **Diseases:** infectious (MESH:D003141), dyspnea (MESH:D004417), tuberculosis (MESH:D014376), Silicosis (MESH:D012829), interstitial lung disease (MESH:D017563)
- **Chemicals:** silica (MESH:D012822), Granite (MESH:C007886)
- **Species:** Histoplasma (genus) [taxon 5036], Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

4 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12116399/full.md

## References

17 references — full list in the complete paper: https://tomesphere.com/paper/PMC12116399/full.md

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Source: https://tomesphere.com/paper/PMC12116399