# Analysis of the Use of Over-the-Counter Therapy for the Prevention and Treatment of COVID-19

**Authors:** Ivan Vukosavljević, Nataša Djorić, Ivana Vukosavljević, Jasmina Milovanović, Nataša Zdravković, Katarina Djordjević, Nebojša Zdravković, Marina Kostić, Ana Barjaktarević, Snezana Cupara, Ivan Čekerevac, Nevena Vasović, Aleksandra Tomić Lučić, Marija Šorak, Nikola Mirković, Olivera Kostić

PMC · DOI: 10.3390/medicina61050803 · 2025-04-25

## TL;DR

This study explores how people used over-the-counter medications and vitamins for self-treatment during the COVID-19 pandemic, finding that younger individuals were more likely to self-medicate.

## Contribution

The study provides insights into the demographics and behaviors of individuals engaging in self-medication during the pandemic.

## Key findings

- Over half of the respondents used over-the-counter medications without a prescription, primarily analgesics.
- Younger, unmarried individuals without income were more likely to self-medicate.
- Vitamin C and D combinations were the most commonly used supplements during the pandemic.

## Abstract

Background and Objectives: Self-medication includes the use of drugs or herbal preparations based on one’s own discretion or the recommendation of another person, often a family member, friend, neighbor, or even a pharmacist, without prior examination and consultation with a doctor. The goal of this study was to determine respondents’ reasons for using self-medication, determine the frequency of self-medication, and analyze differences in respondents’ attitudes about self-medication in relation to several factors. Materials and Methods: The study was conducted as a cross-sectional observational study. The respondents were patients seeking medical examination at the Health Center in Jagodina who had used over-the-counter medications during the COVID-19 pandemic. A total of 175 respondents participated in the study. The study design provided answers to questions about the respondents’ self-medication habits during the COVID-19 pandemic. Results: More than half of the respondents (53.71%) bought medicines without a prescription, with most cases involving analgesics (52.83%). Almost three-quarters of the respondents were completely vaccinated (74.29%) against COVID-19. Additionally, 39.62% of participants used vitamins as part of their self-medication during the COVID-19 pandemic. Among the vitamins, respondents most commonly used a combination of vitamins C and D (20.75%), vitamin D (5.66%), vitamin C (5.66%), and vitamin A (1.89%). Conclusions: Self-medication for the treatment of coronavirus is more often used by younger respondents, who are not yet married, do not have their own income, and rarely visit a doctor. As for supplements, respondents used zinc, and as for vitamins, respondents mostly used a combination of vitamins C and D.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** coronavirus (MESH:D018352), COVID-19 (MESH:D000086382)
- **Chemicals:** zinc (MESH:D015032), vitamin C (MESH:D001205), vitamin D (MESH:D014807), Over (-), vitamin A (MESH:D014801)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12113510/full.md

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Source: https://tomesphere.com/paper/PMC12113510