# Promising Vaccine Formulations for Emerging Infectious Diseases

**Authors:** Pil-Gu Park, Seok-Yong Lee, Hyewon Youn, Kee-Jong Hong

PMC · DOI: 10.3390/ijms26104893 · International Journal of Molecular Sciences · 2025-05-20

## TL;DR

This review discusses the best vaccine formulations for emerging infectious diseases, highlighting the potential of mRNA vaccines.

## Contribution

The paper evaluates and compares vaccine formulations, emphasizing the promise of mRNA vaccines for EIDs.

## Key findings

- Different vaccine formulations have distinct advantages and disadvantages for EID responses.
- mRNA vaccines are considered the most promising for EID vaccines due to their adaptability and effectiveness.
- The review provides a strategy for selecting the most appropriate vaccine formulation based on EID characteristics.

## Abstract

Emerging infectious diseases (EIDs) are one of the greatest threats to human health today, thus requiring an urgent response. Vaccines are one of the most effective means of preventing the spread of infectious diseases, and their usefulness in responding to EIDs has been clearly proven through the process of overcoming the global COVID-19 pandemic. As the characteristics of various vaccine formulations differ, it is necessary to apply the most appropriate one according to the EID response strategy. In this review, we first consider which vaccine formulation is the most suitable for EID vaccines by comparing the pros and cons of different vaccine formulations, and then we discuss the utility of mRNA vaccine formulations, which are considered the most promising for EID vaccines.

## Linked entities

- **Diseases:** COVID-19 (MONDO:0100096)

## Full-text entities

- **Diseases:** COVID-19 (MESH:D000086382), EIDs (MESH:D021821), Infectious Diseases (MESH:D003141)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

109 references — full list in the complete paper: https://tomesphere.com/paper/PMC12112343/full.md

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Source: https://tomesphere.com/paper/PMC12112343