# Predictive Value of Centered Clinical Asymmetric Lower Limb Edema in Diagnosing Deep Vein Thrombosis in Puerperium

## TL;DR

This study identifies clinical indicators that help predict deep vein thrombosis in postpartum women with lower limb swelling.

## Contribution

The study introduces new predictive factors for diagnosing DVT in the puerperium period using specific blood parameters.

## Key findings

- Mean platelet volume (MPV) increases DVT risk 1.497-fold per unit increase.
- Anemia increases DVT risk by 8.46 times.
- Fibrinogen levels are positively correlated with DVT risk.

## Abstract

Background: Peripheral vein thrombosis during pregnancy poses serious diagnostic challenges due to the intertwining of its clinical symptoms with normal pregnancy modifications. Methods: We analyzed and compared the paraclinical test results of singleton pregnant women and women in the first six weeks postpartum who presented with significant lower limb inequality. Results: Our data revealed three predictors of deep vein thrombosis (DVT): mean platelet volume (MPV), with a one-unit increase in MPV being associated with a 1.497-fold higher risk of thrombosis (p = 0.008); platelet distribution width (PDW), with a one-unit decrease in PDW increasing thrombosis risk (odds ratio (OR) = 1.17, p = 0.003); anemia, with its presence increasing the risk of thrombosis by 8.46 times (p = 0.003); and fibrinogen, with a one-unit increase in its level increasing DVT risk 1.003-fold. Conclusions: Significant lower limb inequality might be used as a predictor of DVT during puerperium.