# Blood Chemo-Profiling in Workers Exposed to Occupational Pyrethroid Pesticides

## TL;DR

This study shows that long-term exposure to pyrethroid pesticides at work can lead to significant changes in blood chemistry and increased risk of chronic diseases.

## Contribution

The study identifies a 3.7 times higher risk of chronic disease in workers with prolonged pyrethroid exposure and specific blood profile changes.

## Key findings

- Workers exposed to pyrethroids for over 8 years had a 3.7 times higher risk of chronic diseases.
- Prolonged exposure caused increased gamma-glutamyl transferase (GGT) and decreased albumin levels.
- Blood chemo-profiles changed significantly with extended occupational pyrethroid exposure.

## Abstract

This study investigates the effect of occupational exposure to pyrethroid insecticides on the blood chemo-profiles of workers in the Jazan region. This study was conducted to examine this issue, and workers were divided into exposure groups based on how long they had been employed—from one to two years to more than eight years. Blood samples were analyzed to determine their hematological and biochemical parameters, and their chemo-profiles were assessed by GCMS analysis. Workers exposed for 8+ years had a 3.7 times higher risk of chronic diseases than those exposed for 1–2 years (p < 0.01). Prolonged exposure to pyrethroid pesticides at work is linked to significant changes in blood chemical profiles. While gamma-glutamyl transferase (GGT) levels (p < 0.05) were rather increased by extended exposure times, albumin levels (p < 0.05) showed a significant decrease. These findings suggest re-evaluating and improving workplace safety practices to protect workers from extended pyrethroid exposure.