# Effect of Vascular Photobiomodulation in the Postoperative Period of Alveolar Bone Grafting

**Authors:** Nicole Rosa de Freitas, Luisa Belluco Guerrini, Denise Sabbagh Haddad, Roberta Martinelli de Carvalho, Renato Yassutaka Faria Yaedú, Ana Lúcia Pompéia Fraga de Almeida

PMC · DOI: 10.3390/dj13050190 · Dentistry Journal · 2025-04-26

## TL;DR

This study investigated whether vascular photobiomodulation (VPBM) could reduce pain and swelling after alveolar bone grafting surgery in patients with cleft lip and palate.

## Contribution

The study is one of the first to evaluate VPBM's effects on postoperative pain and temperature in alveolar bone grafting patients.

## Key findings

- VPBM significantly reduced iliac pain compared to placebo and control groups.
- Thermographic analysis showed significantly lower temperature variation in the VPBM group.
- No significant differences were found in facial pain or edema among the groups.

## Abstract

Background/Objectives: This study evaluated the effects of vascular photobiomodulation (VPBM) on pain intensity, edema, and facial temperature variation in patients undergoing alveolar bone grafting (ABG) surgery. Methods: A total of 42 patients with cleft lip and palate (aged 9–25 years) scheduled for ABG using iliac crest bone were randomly assigned in equal numbers (14 per group) to one of three groups: control (ABG only), test (ABG + VPBM), and placebo (ABG + simulated VPBM). Iliac and facial pain and edema were clinically evaluated 24 h post-surgery, along with thermographic facial analysis. Follow-up was conducted via phone calls for one week. Results: No statistically significant differences were observed among the groups regarding facial pain and edema at 24 h post-surgery. However, iliac pain significantly differed between the placebo and control groups (p = 0.045). A significant time-related effect on both facial and iliac pain outcomes was noted during follow-up, irrespective of the group. The need for rescue medication and self-perception of reduced edema did not differ significantly. Thermographic analysis reveals a significantly lower temperature variation in the test group (2.36 °C) compared to the other groups (p = 0.007). Conclusions: Overall, VPBM therapy influenced postoperative pain in the early recovery phase and temperature in the immediate postoperative period but did not significantly affect edema.

## Linked entities

- **Diseases:** cleft lip and palate (MONDO:0016044)

## Full-text entities

- **Diseases:** cleft lip and palate (MESH:D002971), edema (MESH:D004487), pain (MESH:D010146), postoperative pain (MESH:D010149), facial pain (MESH:D005157), iliac pain (MESH:D017543)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

7 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12110624/full.md

## References

24 references — full list in the complete paper: https://tomesphere.com/paper/PMC12110624/full.md

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Source: https://tomesphere.com/paper/PMC12110624