# Transporting Blood to Remote Areas: The Impact of Blood Shaker Machine Vibration on the Quality of Erythrocytes, Hemoglobin, and Lactate Dehydrogenase Levels

**Authors:** Jeffri Ardiyanto, Jessica Juan Pramudita, M Syamsul Arif Setiyo Negoro, Slamet Wardoyo

PMC · DOI: 10.4314/ejhs.v34i6.10 · Ethiopian Journal of Health Sciences · 2024-11-01

## TL;DR

This study examines how vibrations during transport affect blood quality, showing that different vibration frequencies can damage red blood cells and hemoglobin.

## Contribution

The study provides new empirical evidence on how specific vibration frequencies impact erythrocyte and hemoglobin levels during blood transport.

## Key findings

- 6 Hz vibration significantly reduced erythrocyte levels compared to control and 11 Hz groups.
- 11 Hz vibration caused significantly lower hemoglobin levels than both control and 6 Hz groups.
- LDH levels varied significantly among the treatment groups, indicating cell damage from vibrations.

## Abstract

Effective transportation of blood is essential for ensuring accessible and
high-quality blood for transfusion. However, vibration can have a negative
impact on blood quality, leading to the loss of erythrocytes and hemoglobin.
The aim of the study was to analyse the effect of different vibration
exposures for 15 minutes on erythrocyte, haemoglobin and lactate
dehydrogenase (LDH) levels of blood samples.

A quasi-experimental study was conducted on blood donors at the Semarang,
Central Java, unit vehicle of the Indonesian Red Cross. Blood samples were
collected from donors and exposed to different vibration frequencies for 15
minutes. The erythrocyte, hemoglobin, and lactate dehydrogenase (LDH) levels
of the blood samples were then measured. Tests were carried out on three
treatment groups, namely control, 6 Hz vibration, and 11 Hz with 30 bags of
blood tested with each treatment group of 10 samples.

The results showed that vibration had a significant impact on the integrity
of erythrocytes and hemoglobin in whole blood The group exposed to 6 Hz
vibration had significantly lower erythrocyte levels than the control group
and the group exposed to 11 Hz vibration. The hemoglobin levels after
treatment also varied significantly between treatment cohorts, with
significantly lower hemoglobin levels observed in the 11 Hz vibration group
compared to both the control group and the 6 Hz vibration group. In
addition, there was a significant difference between the LDH levels of the
various groups following treatment.

The findings of this study suggested that vibration can have a negative
impact on blood quality, leading to the loss of erythrocytes and hemoglobin.
To protect blood product integrity and reduce the risk of
transfusion-related losses, it is essential to implement appropriate
vibration mitigation strategies during blood product transport.

## Full-text entities

- **Genes:** HP (haptoglobin) [NCBI Gene 3240] {aka HP2ALPHA2, HPA1S}
- **Diseases:** blood quality loss (MESH:D016063), Hemolysis (MESH:D006461), infectious disease (MESH:D003141), tissue injury (MESH:D017695), ATP deficiency (OMIM:614052), membrane (MESH:D015433)
- **Chemicals:** bilirubin (MESH:D001663), oxygen (MESH:D010100), NO (MESH:D009614), ROS (MESH:D017382), ATP (MESH:D000255)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12110271/full.md

## References

28 references — full list in the complete paper: https://tomesphere.com/paper/PMC12110271/full.md

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Source: https://tomesphere.com/paper/PMC12110271