# Precision Medicine and the Human Proteome in Disease, Diagnostics and Translation: Current Status and Future Prospects

**Authors:** M. Walid Qoronfleh

PMC · DOI: 10.3390/biomedicines13051130 · Biomedicines · 2025-05-07

## TL;DR

This paper discusses how studying the human proteome helps understand diseases, improve diagnostics, and develop personalized treatments.

## Contribution

The paper provides an overview of the current status and future potential of human proteome research in precision medicine.

## Key findings

- Proteome research is crucial for understanding disease mechanisms and developing diagnostics.
- Advancements in proteomics are enabling personalized treatment strategies.
- Future prospects include improved therapeutic interventions through deeper proteome insights.

## Abstract

The human proteome—the entire collection of proteins expressed by the human genome—represents a dynamic and intricate landscape of biological function. Proteins are the workhorses of the body, driving processes from cellular communication to immune defense, and their alterations underpin many diseases. Understanding the proteome has become a cornerstone of modern biomedical research, offering insights into disease mechanisms, diagnostic tools, and personalized treatments through precision medicine. This commentary explores the current state of human proteome research; its applications in disease understanding, diagnostics, and therapeutic advancements; and the exciting prospects that lie ahead.

## Full-text entities

- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## References

13 references — full list in the complete paper: https://tomesphere.com/paper/PMC12109353/full.md

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Source: https://tomesphere.com/paper/PMC12109353