# New imaging findings of tumor invasion into brain tissue: “Peritumoral Hyperintense Enhancement Sign”

## TL;DR

This study identifies a new MRI sign that indicates brain tumor invasion, helping improve treatment planning and prognosis.

## Contribution

The study introduces the 'Peritumoral Hyperintense Enhancement Sign' as a novel MRI marker for brain invasion.

## Key findings

- The 'Peritumoral Hyperintense Enhancement Sign' is associated with brain invasion confirmed by histopathology.
- The sign appears in various MRI patterns, including flame-shaped and crescentic enhancements.
- This MRI feature aids in treatment planning and may improve patient outcomes.

## Abstract

This study investigated the MRI characteristics of meningiomas and brain metastases, exploring the relationship between the “Peritumoral Hyperintense Enhancement Sign” and brain invasion, and its clinical implications for treatment planning.

A multicenter retrospective analysis was conducted on 24 cases (17 brain metastases and 7 meningiomas), examining the MRI features of the “Peritumoral Hyperintense Enhancement Sign” and corresponding histopathological characteristics.

All cases demonstrated peritumoral enhancement: 8 cases exhibited flame-shaped enhancement, 12 showed crescentic enhancement, and 4 displayed both patterns. Histopathological analysis confirmed brain invasion in regions showing abnormal enhancement.

The “Peritumoral Hyperintense Enhancement Sign” not only serves as a valuable indicator of brain invasion and provides guidance for clinical target delineation in treatment planning, but also facilitates more precise treatment planning and may contribute to improved prognostic assessment and reduced recurrence risk.