# Single-Stage Quadruple Valve Replacement with Mechanical and Bioprosthetic Valves: An 8-Year Follow-up Study from India

**Authors:** Akriti Gera, Amit Misri, Pankaj Bajpai, Rajesh Sharma, Anil Bhan

PMC · DOI: 10.1055/a-2591-9608 · The Thoracic and Cardiovascular Surgeon Reports · 2025-05-26

## TL;DR

A 23-year-old man successfully underwent a complex heart surgery in India and remained healthy for 8 years with no complications.

## Contribution

This is the longest reported follow-up of a quadruple valve replacement in India.

## Key findings

- The patient remained asymptomatic with no valve-related complications for 8 years.
- Cardiac function improved significantly after the surgery.
- Single-stage quadruple valve replacement showed a good long-term outcome.

## Abstract

Congenital heart disease, repaired or unrepaired, requires lifelong follow-up. Carcinoid disease, rheumatic heart disease, and infective endocarditis can damage all four cardiac valves. Multiple valve replacement has a poor outcome.

A 23-year-old male underwent single-stage quadruple valve (mechanical [mitral and aortic] and bioprosthetic [tricuspid and pulmonary]) replacement due to rheumatic carditis and surgical complications. Over 8 years of follow-up, he is asymptomatic, has no prosthetic valve-related complications, and has improved cardiac function.

Single-stage quadruple valve replacement with mechanical and bioprosthetic valves has a good long-term outcome. To the best of our knowledge, this is the longest follow-up study from India.

## Linked entities

- **Diseases:** rheumatic heart disease (MONDO:0006955), rheumatic carditis (MONDO:0006955), congenital heart disease (MONDO:0005453), infective endocarditis (MONDO:0000565)

## Full-text entities

- **Diseases:** rheumatic heart disease (MESH:D012214), rheumatic carditis (MESH:D009205), Congenital heart disease (MESH:D006330), infective endocarditis (MESH:D004696), Carcinoid disease (MESH:D002276)

## Full text

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## Figures

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## References

12 references — full list in the complete paper: https://tomesphere.com/paper/PMC12105931/full.md

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Source: https://tomesphere.com/paper/PMC12105931