# Mild Encephalitis/Encephalopathy With a Reversible Splenial Lesion (MERS) in an Adult Following Influenza A Infection

## TL;DR

A 27-year-old woman developed neurological symptoms after an influenza A infection, leading to a rare brain condition called MERS, which resolved without corticosteroid treatment.

## Contribution

This paper reports a rare adult case of MERS following influenza A, emphasizing its self-limiting nature and diagnostic challenges in adults.

## Key findings

- An MRI revealed a hyperintense splenial lesion in the corpus callosum consistent with MERS.
- The patient fully recovered without corticosteroid treatment.
- The case highlights the importance of recognizing MERS to avoid unnecessary interventions in adults.

## Abstract

Mild encephalitis/encephalopathy with a reversible splenial lesion (MERS) is a rare clinical-radiological entity predominantly reported in pediatric populations, with limited cases in adults. We present a case of a 27-year-old female who developed transient neurological deficits following influenza A infection. She presented with severe headache, neck stiffness, and limb weakness with sensory deficits. Initial suspicion of meningoencephalitis prompted treatment with intravenous antibiotics and antivirals. However, an MRI revealed a hyperintense splenial lesion in the corpus callosum (SCC), supporting a diagnosis of MERS. The patient achieved full recovery without corticosteroids, reinforcing the self-limiting nature of this condition. This case highlights the diagnostic challenges, imaging findings, and management considerations of MERS, underscoring the importance of clinical awareness to avoid unnecessary interventions in adult cases.