# Protective effects of dietary nutrients on hearing loss: a systematic review and meta-analysis

## TL;DR

This study finds that certain nutrients like vitamin B2 and antioxidants may help prevent hearing loss, suggesting diet could play a role in auditory health.

## Contribution

The study provides a systematic review and meta-analysis linking specific dietary nutrients to reduced hearing loss risk.

## Key findings

- Higher intake of vitamin B2, β-carotene, and carotenoids is associated with lower hearing loss risk.
- Fish, fiber, and protein consumption may protect against hearing loss.
- Antioxidants appear to play a key role in preserving auditory function.

## Abstract

Hearing loss ranks as the third most prevalent disability globally, significantly impacting individuals and society, and imposing a substantial healthcare burden. The World Health Organization reports that over 1.5 billion people worldwide experience hearing loss, with one-third of these cases attributed to preventable factors. Recently, the influence of diet and nutrition on auditory health has garnered increasing attention.

This study systematically reviews and meta-analyzes the protective effects of dietary nutrients on hearing, examining specific nutrients' impact on hearing loss and their potential biological mechanisms.

A comprehensive search of PubMed, Embase, Web of Science, and the Cochrane Library was conducted for relevant studies up to August 2024. Following PRISMA guidelines, the systematic review was registered in PROSPERO. Included were observational studies assessing the relationship between dietary intake and hearing loss.

Thirty-three studies met inclusion criteria: 21 cross-sectional, 10 cohort, and 2 case-control studies. Meta-analysis revealed significant inverse associations between the intake of vitamin B2, β-carotene, carotenoids, β-cryptoxanthin, fat, protein, fiber, and fish, and the risk of hearing loss.

Certain dietary nutrients may protect hearing health. Increasing intake of antioxidants, fiber, protein, and fish rich in unsaturated fatty acids may help preserve auditory function.Keywords: Hearing loss, dietary nutrients, systematic review, meta-analysis, antioxidants.

https://www.crd.york.ac.uk/PROSPERO/view/CRD42024572118, identifier: CRD42024572118.