# High-velocity nasal insufflation in dogs with left-sided congestive heart failure unresponsive to traditional oxygen therapy: a retrospective case series

**Authors:** Bailey Lane, Rebecca A. Walton, April E. Blong, Meredith ‘t Hoen, Melissa A. Tropf, Jessica L. Ward, Allison K. Masters

PMC · DOI: 10.3389/fvets.2025.1562633 · Frontiers in Veterinary Science · 2025-05-09

## TL;DR

This study explores high-velocity nasal insufflation as a treatment for dogs with heart failure who do not respond to traditional oxygen therapy.

## Contribution

The study introduces high-velocity nasal insufflation as a novel oxygen support method for dogs with left-sided congestive heart failure.

## Key findings

- All dogs successfully discontinued from high-velocity nasal insufflation survived to discharge.
- Two dogs euthanized had Stage D refractory congestive heart failure.
- No major complications were observed with high-velocity nasal insufflation use.

## Abstract

To describe high–velocity nasal insufflation (HVNI) for managing dogs with left–sided congestive heart failure (L–CHF) failing traditional oxygen therapy (TOT). To secondarily evaluate complications based on retrospective evaluation of the record of HVNI and survival to discharge.

Retrospective case series from a university teaching hospital between August 2019 and October 2021.

Twelve dogs diagnosed with L-CHF and managed with HVNI.

Medical records were retrospectively reviewed for signalment, point-of-care diagnostics, and HVNI information. Nine dogs were diagnosed with myxomatous mitral valve disease, and three dogs were diagnosed with dilated cardiomyopathy. All dogs in this study required HVNI after failing TOT. Dogs were treated with HVNI for a median of 14 h (range 2–22 h). HVNI was successfully discontinued in 10 dogs (83%), all of which survived to discharge. Two dogs on HVNI were humanely euthanized, both of which were diagnosed with Stage D refractory CHF. No major complications of HVNI were noted in any dogs.

HVNI is a potential method of escalating oxygen support for dogs in L-CHF who fail TOT. In this case series, all dogs in which HVNI was successfully discontinued survived to discharge.

## Linked entities

- **Diseases:** dilated cardiomyopathy (MONDO:0005021)

## Full-text entities

- **Diseases:** congestive heart failure (MESH:D006333), myxomatous mitral valve disease (MESH:C564326), dilated cardiomyopathy (MESH:D002311), L (MESH:D007926)
- **Chemicals:** oxygen (MESH:D010100)
- **Species:** Canis lupus familiaris (dog, subspecies) [taxon 9615]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12098610/full.md

## References

18 references — full list in the complete paper: https://tomesphere.com/paper/PMC12098610/full.md

---
Source: https://tomesphere.com/paper/PMC12098610