# Comparative analysis of influenza healthcare disparities in the United States using retrospective administrative claims from Medicaid and commercial databases, 2015–2019

**Authors:** Jennifer L. Matas, Kira Raskina, Sabine Tong, Derrick Forney, Bruno Scarpellini, Mario Cruz-Rivera, Gary Puckrein, Liou Xu

PMC · DOI: 10.1371/journal.pone.0321208 · PLOS One · 2025-05-22

## TL;DR

This study compares how Medicaid and commercially insured patients in the U.S. use healthcare services for influenza, finding disparities in emergency department visits and antiviral prescriptions.

## Contribution

The study provides new insights into healthcare disparities in influenza management between Medicaid and commercial insurance populations.

## Key findings

- Medicaid patients had higher rates of influenza-related emergency department visits compared to commercially insured patients.
- A larger proportion of Medicaid beneficiaries did not fill influenza antiviral prescriptions compared to commercially insured patients.
- Non-Hispanic Black and Hispanic patients had the highest rates of influenza-related emergency department visits in both populations.

## Abstract

Influenza-related healthcare utilization among Medicaid patients and commercially insured patients is not well-understood. This study compared influenza-related healthcare utilization and assessed disease management among individuals diagnosed with influenza during the 2015–2019 influenza seasons.

This retrospective cohort study identified influenza cases among adults (18–64 years) using data from the Transformed Medicaid Statistical Information System (T-MSIS) Analytic Files (TAF) Research Identifiable Files (RIF) and Optum’s de-identified Clinformatics® Data Mart Database (CDM). Influenza-related healthcare utilization rates were calculated per 100,000 patients by setting (outpatient, emergency department (ED), inpatient hospitalizations, and intensive care unit (ICU) admissions) and demographics (sex, race, and region). Rate ratios were computed to compare results from both databases. Influenza episode management assessment included the distribution of the index point-of-care, antiviral prescriptions, and laboratory tests obtained.

The Medicaid population had a higher representation of racial/ethnic minorities than the CDM population. In the Medicaid population, influenza-related visits in outpatient and ED settings were the most frequent forms of healthcare utilization, with similar rates of 652 and 637 visits per 100,000, respectively. In contrast, the CDM population predominantly utilized outpatient settings. Non-Hispanic Blacks and Hispanics exhibited the highest rates of influenza-related ED visits in both cohorts. In the Medicaid population, Black (64.5%) and Hispanic (51.6%) patients predominantly used the ED as their index point-of-care for influenza. Overall, a greater proportion of Medicaid beneficiaries (49.8%) did not fill any influenza antiviral prescription compared to the CDM population (37.0%).

Addressing disparities in influenza-related healthcare utilization between Medicaid and CDM populations is crucial for equitable healthcare access. Targeted interventions are needed to improve primary care and antiviral access and reduce ED reliance, especially among racial/ethnic minorities and low-income populations.

## Linked entities

- **Diseases:** influenza (MONDO:0005812)

## Full-text entities

- **Diseases:** Influenza (MESH:D007251)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

56 references — full list in the complete paper: https://tomesphere.com/paper/PMC12097570/full.md

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Source: https://tomesphere.com/paper/PMC12097570