# Pyoderma Grangrenosum

**Authors:** Reza Aghaei, Edmund Hsu, Christopher McCoy

PMC · DOI: 10.5811/cpcem.1675 · Clinical Practice and Cases in Emergency Medicine · 2025-02-26

## TL;DR

A middle-aged woman with ulcerative colitis developed painful leg ulcers diagnosed as pyoderma gangrenosum after a thorough evaluation.

## Contribution

The paper presents a clinical case illustrating the characteristics and diagnosis of pyoderma gangrenosum.

## Key findings

- Pyoderma gangrenosum ulcers were identified in a patient with ulcerative colitis.
- Clinical and pathological assessments confirmed the diagnosis of pyoderma gangrenosum.
- The case highlights the importance of a thorough evaluation for accurate diagnosis.

## Abstract

We describe a middle-aged female with past medical history of ulcerative colitis presenting to the emergency department with bilateral painful ulcers rapidly growing on her lower legs in the prior four weeks. She was consulted by a dermatologist and after a thorough clinical and pathology assessment (as a diagnosis of exclusion), treatment for pyoderma gangrenosum was started.

Pyoderma gangrenosum is a painful, chronic, ulcerative disorder often occurring in association with systemic disease. We review the clinical presentation of pyoderma gangrenosum and its complications. We describe the characteristics of ulcers with pictures from the patient. Our case illustrates the findings of pyoderma gangrenosum both clinically and pathologically.

## Linked entities

- **Diseases:** ulcerative colitis (MONDO:0005101), pyoderma gangrenosum (MONDO:0018824)

## Full-text entities

- **Diseases:** ulcerative colitis (MESH:D003093), systemic disease (MESH:D034721), Pyoderma Grangrenosum (MESH:D011711), Pyoderma gangrenosum (MESH:D017511), ulcerative disorder (MESH:D014456)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

3 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12097255/full.md

## References

5 references — full list in the complete paper: https://tomesphere.com/paper/PMC12097255/full.md

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Source: https://tomesphere.com/paper/PMC12097255