# Perinatal Stroke Presenting as Arm Swelling: A Case Report

**Authors:** Sarah K. Sylvester, Amber M. Morse, Ryan C. Kwong

PMC · DOI: 10.5811/cpcem.21246 · Clinical Practice and Cases in Emergency Medicine · 2025-02-15

## TL;DR

A newborn presented with arm swelling and was later diagnosed with perinatal stroke, highlighting the need for early recognition of this rare condition.

## Contribution

This case report raises awareness of atypical perinatal stroke presentations and emphasizes timely diagnosis and management.

## Key findings

- A term neonate presented with left arm swelling and abnormal tone, later diagnosed with perinatal stroke.
- Imaging revealed thrombi in the left axillary and subclavian arteries and infarction in cerebral arteries.
- The case underscores the importance of prompt recognition to improve outcomes in perinatal stroke.

## Abstract

Perinatal stroke is a rare but clinically significant condition that can present in a variety of ways and can result in diagnostic challenges in a particularly vulnerable population. We present the case of a term neonate who presented with left arm swelling, ultimately diagnosed with perinatal stroke.

A term male neonate presented to the emergency department with left arm swelling noted the day prior, with abnormal tone of the left arm since birth. Physical examination revealed mild erythema and edema localized to the left upper extremity, with the arm held in flexion. Neurological examination was otherwise unremarkable. Further evaluation, including imaging studies, demonstrated thrombi in the left axillary and subclavian arteries, as well as an infarct involving the right middle cerebral artery and anterior cerebral artery with diffusion restriction, consistent with perinatal stroke.

Through this case report, we aimed to increase awareness of perinatal stroke among healthcare professionals and highlight the importance of prompt recognition and appropriate management in optimizing outcomes for affected infants.

## Full-text entities

- **Diseases:** abnormal tone (MESH:D009122), Arm Swelling (MESH:D001134), edema (MESH:D004487), infarct (MESH:D007238), Perinatal Stroke (MESH:D066087), erythema (MESH:D004890)

## Full text

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## Figures

2 figures with captions in the complete paper: https://tomesphere.com/paper/PMC12097252/full.md

## References

4 references — full list in the complete paper: https://tomesphere.com/paper/PMC12097252/full.md

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Source: https://tomesphere.com/paper/PMC12097252