# Editorial: Decoding cell fate: the critical roles of extracellular vesicles

**Authors:** Yongqiang Chen, Saeid Ghavami, Paul C. Park, Joy Irobi

PMC · DOI: 10.3389/fcell.2025.1615951 · Frontiers in Cell and Developmental Biology · 2025-05-08

## Full-text entities

- **Genes:** PTEN (phosphatase and tensin homolog) [NCBI Gene 5728] {aka 10q23del, BZS, CWS1, DEC, GLM2, MHAM}, HMOX1 (heme oxygenase 1) [NCBI Gene 3162] {aka HMOX1D, HO-1, HSP32, bK286B10}, PINK1 (PTEN induced kinase 1) [NCBI Gene 65018] {aka BRPK, PARK6}, NFE2L2 (NFE2 like bZIP transcription factor 2) [NCBI Gene 4780] {aka IMDDHH, NRF2, Nrf-2}
- **Diseases:** inflammation (MESH:D007249), degenerative joint disease (MESH:D019636), OA (MESH:D010003), SSc (MESH:D012595), joint dysfunction (MESH:D007592), autoimmune disease (MESH:D001327), pain (MESH:D010146), vasculopathy (MESH:D000090122), articular cartilage damage (MESH:D002357), immune dysfunction (MESH:D007154), fibrosis (MESH:D005355), PCP (MESH:D011020), cancer (MESH:D009369), diabetes (MESH:D003920)
- **Chemicals:** Rhizoma Drynariae (-), lipids (MESH:D008055)
- **Species:** Homo sapiens (human, species) [taxon 9606], Gynochthodes officinalis (ba ji, species) [taxon 266091]

## Full text

_Full body text omitted from this summary view._ Fetch the complete paper as Markdown: https://tomesphere.com/paper/PMC12095917/full.md

## Figures

1 figure with captions in the complete paper: https://tomesphere.com/paper/PMC12095917/full.md

## References

9 references — full list in the complete paper: https://tomesphere.com/paper/PMC12095917/full.md

---
Source: https://tomesphere.com/paper/PMC12095917