# Biomechanical risk factors for ACL injury during a high-intensity exergame differ between the sexes based on exercise type

**Authors:** Michelle C. Haas, Anna L. Martin-Niedecken, Larissa Wild, Leander Schneeberger, Eveline S. Graf

PMC · DOI: 10.1371/journal.pone.0324702 · PLOS One · 2025-05-21

## TL;DR

The study found that men and women move differently during a high-intensity video game exercise, which could help reduce ACL injuries in women.

## Contribution

The study identifies sex-specific biomechanical differences during exergaming that could inform injury prevention and rehabilitation.

## Key findings

- Females showed higher knee internal rotation angles than males during certain exercises.
- Sex differences in movement patterns were observed in touches and punches exercises.
- These findings suggest the need for sex-specific training approaches in ACL injury prevention.

## Abstract

Incidence rates in anterior cruciate ligament injuries, which are linked to multiple factors, are higher in females than in males. Modifiable contributors to the difference in risk are biomechanical factors such as knee valgus and knee rotation or neuromuscular control. Despite considerable research efforts, re-rupture rates are still high necessitating the need for improved risk reduction and rehabilitation programs. Incorporating exergaming, physically active serious games including a dual-task, has high potential to address this need. However, the execution of dual-tasks leads to altered movement patterns. Consequently, a comprehensive understanding of these movement patterns and their sex-specific differences is essential to subsequently tailor the training approach. The aim of this study was to explore biomechanical differences between males and females when performing a high-intensive exergame. Using three-dimensional motion capture (Vicon) during a 25-min exergame (Sphery Racer, ExerCube), kinematics were measured in 18 healthy athletes (9 male, 9 female). Knee valgus, knee internal rotation, and hip flexion angles during 10–30° knee flexion, were compared between the sexes and in each of the nine different exercises. Touches, and punches showed significant sex differences for knee internal rotation angle (main effect of sex F(1,16) = 6.14, p = .025). Depending on the exercise and side, the difference in estimated means between males and females in touches and punches ranged from 4.6–7.8°, with females showing higher values. Therefore, females display distinct movement patterns linked to anterior cruciate ligament injury, indicating that these movements should be carefully integrated into routine training and late-stage post-injury rehabilitation.

## Full-text entities

- **Diseases:** rupture (MESH:D012421), Knee valgus (MESH:D007718), ACL injury (MESH:D000070598)

## Full text

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## Figures

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## References

60 references — full list in the complete paper: https://tomesphere.com/paper/PMC12094794/full.md

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Source: https://tomesphere.com/paper/PMC12094794