# Regional anesthesia in colorectal laparoscopy: a retrospective comparison of quadratus lumborum and TAP blocks

**Authors:** Mihaela Roxana Oliță, Mihai Adrian Eftimie, Andrei Andreșanu, Mihai Adrian Dobra, Elena Liliana Mirea, Dana Rodica Tomescu

PMC · DOI: 10.25122/jml-2025-0067 · Journal of Medicine and Life · 2025-04-01

## TL;DR

This study compares two regional anesthesia techniques for laparoscopic colorectal surgery and finds that the quadratus lumborum block provides better pain control and faster recovery.

## Contribution

The study provides new evidence that quadratus lumborum blocks are more effective than TAP blocks for postoperative pain management in colorectal surgery.

## Key findings

- QL block patients used significantly less opioids and had longer time to first analgesic request.
- QL block was associated with shorter hospital stays and reduced non-opioid analgesic use.
- QL block outperformed TAP and no-block groups in multiple pain-related outcomes.

## Abstract

Effective postoperative pain control is pivotal in enhancing recovery following laparoscopic colorectal surgery. Regional anesthesia techniques such as the transversus abdominis plane (TAP) block and the quadratus lumborum (QL) block have gained prominence as components of multimodal analgesia. However, their comparative efficacy remains underexplored. This retrospective observational cohort study analyzed data from 289 patients undergoing laparoscopic colon surgery. Patients were stratified into three groups: TAP block (Group A, n = 54), QL block (Group B, n = 62), and no regional block (Group C, n = 173). Primary endpoints included time to first analgesic administration and total analgesic consumption (opioids and non-opioids). Statistical analyses were conducted using R (v4.4.2) and Jamovi (v2.3), with significance set at P < 0.05. Group B (QL block) demonstrated significantly reduced opioid consumption (mean 13.16 ± 2.69 mg) compared to both Group A (16.80 ± 5.51 mg) and Group C (18.03 ± 4.29 mg), P < 0.001. Time to first analgesic request was longer in Group B (16.06 ± 2.53 h), indicating more durable analgesia. Non-opioid usage (paracetamol, tramadol, nefopam) was similarly lower in Group B across all comparisons (P < 0.001). Group B also exhibited a significantly shorter hospital stay (4.87 ± 1.14 days) relative to Groups A and C. The QL block was associated with superior postoperative analgesia, reduced opioid and adjunct analgesic requirements, prolonged pain-free intervals, and accelerated postoperative recovery in laparoscopic colorectal surgery. These findings underscore QL block as a potent element of opioid-sparing, multimodal analgesic strategies and support its broader adoption in enhanced recovery protocols.

## Full-text entities

- **Diseases:** postoperative pain (MESH:D010149), TAP block (MESH:D006327), pain (MESH:D010146)
- **Chemicals:** nefopam (MESH:D009340), paracetamol (MESH:D000082), tramadol (MESH:D014147)
- **Species:** Homo sapiens (human, species) [taxon 9606]

## Full text

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## Figures

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## References

31 references — full list in the complete paper: https://tomesphere.com/paper/PMC12094314/full.md

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Source: https://tomesphere.com/paper/PMC12094314