# Rendu-Osler disease, a cause of recurrent epistaxis: a case report

## TL;DR

This case report discusses Rendu-Osler disease, a rare condition causing recurring nosebleeds and other vascular issues, emphasizing the need for personalized treatment.

## Contribution

The paper contributes a case report highlighting the importance of individualized treatment for Rendu-Osler disease.

## Key findings

- Rendu-Osler disease presents with recurrent epistaxis, iron deficiency, and anemia.
- Treatment must consider both local and systemic manifestations of the disease.
- Individualized care is essential due to the condition's diverse clinical features.

## Abstract

Rendu-Osler disease is a rare, autosomal dominant vascular malformation disorder with diverse clinical manifestations. It commonly presents with recurrent epistaxis, iron deficiency, and secondary anemia. The condition affects small vessels in the nasal, oral, and gastrointestinal mucosa, the skin of the face, lips, and fingertips, and solid organs. This article discusses general and specific manifestations of the disease, along with its general and particular management. A case presentation is included to demonstrate that treatment must be individualized, taking into account all aspects of the condition, including local and systemic manifestations, comorbidities, and the patient’s chronic treatment.